AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer's Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons

Increasing evidence suggests that mitochondrial functions are altered in AD and play an important role in AD pathogenesis. It has been established that H(2)S homeostasis is balanced in AD. The emerging mitochondrial roles of H(2)S include antioxidation, antiapoptosis, and the modulation of cellular...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Zhao, Feng-li, Fang, Fang, Qiao, Pei-feng, Yan, Ning, Gao, Dan, Yan, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753001/
https://ncbi.nlm.nih.gov/pubmed/27057285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8360738
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