Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding

One of the goals of HIV-1 vaccine development is the elicitation of neutralizing antibodies against vulnerable regions on the envelope glycoprotein (Env) viral spike. Broadly neutralizing antibodies targeting the Env glycan-V3 region (also called the N332 glycan supersite) have been described previo...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Longo, Nancy S., Sutton, Matthew S., Shiakolas, Andrea R., Guenaga, Javier, Jarosinski, Marissa C., Georgiev, Ivelin S., McKee, Krisha, Bailer, Robert T., Louder, Mark K., O'Dell, Sijy, Connors, Mark, Wyatt, Richard T., Mascola, John R., Doria-Rose, Nicole A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2016
Gaiak:
Pathogenesis and Immunity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110179/
https://ncbi.nlm.nih.gov/pubmed/27654288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01012-16
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