Dexamethasone rapidly suppresses IL-33-stimulated mast cell function by blocking transcription factor activity

Mast cells are critical effectors of allergic disease and can be activated by IL-33, a proinflammatory member of the IL-1 cytokine family. IL-33 worsens the pathology of mast cell–mediated diseases, but therapies to antagonize IL-33 are still forthcoming. Because steroids are the mainstay of allergi...

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Bibliografski detalji
Izdano u:J Leukoc Biol
Glavni autori: Paranjape, Anuya, Chernushevich, Oksana, Qayum, Amina Abdul, Spence, Andrew J., Taruselli, Marcela T., Abebayehu, Daniel, Barnstein, Brian O., McLeod, Jamie Josephine Avila, Baker, Bianca, Bajaj, Gurjas S., Chumanevich, Alena P., Oskeritzian, Carole A., Ryan, John J.
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2016
Teme:
Inflammation, Extracellular Mediators, & Effector Molecules
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109997/
https://ncbi.nlm.nih.gov/pubmed/27443878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0316-125R
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