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Cocrystal transition points: Role of cocrystal solubility, drug solubility, and solubilizing agents

In this manuscript we bring together concepts that are relevant to the solubilization and thermodynamic stability of cocrystals in the presence of drug solubilizing agents. Simple equations are derived that allow calculation of cocrystal solubilization and transition point solubility. Analysis of 10...

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Bibliografische gegevens
Gepubliceerd in:Mol Pharm
Hoofdauteurs: Lipert, Maya, Rodríguez-Hornedo, Naír
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109980/
https://ncbi.nlm.nih.gov/pubmed/26207517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00111
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