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Cocrystal transition points: Role of cocrystal solubility, drug solubility, and solubilizing agents

In this manuscript we bring together concepts that are relevant to the solubilization and thermodynamic stability of cocrystals in the presence of drug solubilizing agents. Simple equations are derived that allow calculation of cocrystal solubilization and transition point solubility. Analysis of 10...

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Bibliografski detalji
Izdano u:Mol Pharm
Glavni autori: Lipert, Maya, Rodríguez-Hornedo, Naír
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109980/
https://ncbi.nlm.nih.gov/pubmed/26207517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00111
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