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Understanding the differences between cocrystal and salt aqueous solubilities
This work challenges the popular notion that pharmaceutical salts are more soluble than cocrystals. There are cocrystals that are more soluble than salt forms of a drug and vice-versa. It all depends on the interplay between the chemistry of both the solid and solution phases. Aqueous solubility, pH...
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| Publicado no: | J Pharm Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5774673/ https://ncbi.nlm.nih.gov/pubmed/29097226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.10.033 |
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