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Cocrystals to facilitate delivery of poorly soluble compounds beyond-rule-of-5

Besides enhancing aqueous solubilities, cocrystals have the ability to fine-tune solubility advantage over drug, supersaturation index, and bioavailability. This review presents important facts about cocrystals that sets them apart from other solid-state forms of drugs, and a quantitative set of rul...

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Bibliografiska uppgifter
I publikationen:Adv Drug Deliv Rev
Huvudupphovsmän: Kuminek, Gislaine, Cao, Fengjuan, de Oliveira da Rocha, Alanny Bahia, Cardoso, Simone Gonçalves, Rodríguez-Hornedo, Naír
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910885/
https://ncbi.nlm.nih.gov/pubmed/27137109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2016.04.022
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