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Cocrystals to facilitate delivery of poorly soluble compounds beyond-rule-of-5
Besides enhancing aqueous solubilities, cocrystals have the ability to fine-tune solubility advantage over drug, supersaturation index, and bioavailability. This review presents important facts about cocrystals that sets them apart from other solid-state forms of drugs, and a quantitative set of rul...
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| Publié dans: | Adv Drug Deliv Rev |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4910885/ https://ncbi.nlm.nih.gov/pubmed/27137109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2016.04.022 |
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