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Cocrystal solubilization in biorelevant media and its prediction from drug solubilization

This work examines cocrystal solubility in biorelevant media, (FeSSIF, fed state simulated intestinal fluid), and develops a theoretical framework that allows for the simple and quantitative prediction of cocrystal solubilization from drug solubilization. The solubilities of four hydrophobic drugs a...

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Bibliografische gegevens
Gepubliceerd in:J Pharm Sci
Hoofdauteurs: Lipert, Maya P., Roy, Lilly, Childs, Scott L., Rodríguez-Hornedo, Naír
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706795/
https://ncbi.nlm.nih.gov/pubmed/26390213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24640
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