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Cocrystal solubilization in biorelevant media and its prediction from drug solubilization
This work examines cocrystal solubility in biorelevant media, (FeSSIF, fed state simulated intestinal fluid), and develops a theoretical framework that allows for the simple and quantitative prediction of cocrystal solubilization from drug solubilization. The solubilities of four hydrophobic drugs a...
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| Publicado no: | J Pharm Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4706795/ https://ncbi.nlm.nih.gov/pubmed/26390213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24640 |
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