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How PEGylation Influences Protein Conformational Stability

PEGylation is an important strategy for enhancing the pharmacokinetic properties of protein therapeutics. The development of chemoselective side-chain modification reactions has enabled researchers to PEGylate proteins with high selectivity at defined locations. However, aside from avoiding active s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Curr Opin Chem Biol
Päätekijät: Lawrence, Paul B., Price, Joshua L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107330/
https://ncbi.nlm.nih.gov/pubmed/27580482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2016.08.006
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