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How PEGylation Influences Protein Conformational Stability
PEGylation is an important strategy for enhancing the pharmacokinetic properties of protein therapeutics. The development of chemoselective side-chain modification reactions has enabled researchers to PEGylate proteins with high selectivity at defined locations. However, aside from avoiding active s...
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| Publicado no: | Curr Opin Chem Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5107330/ https://ncbi.nlm.nih.gov/pubmed/27580482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2016.08.006 |
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