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Acyclic nucleoside phosphonates containing the amide bond
ABSTRACT: To study the influence of a linker rigidity and donor–acceptor properties, the P–CH(2)–O–CHR– fragment in acyclic nucleoside phosphonates (e.g., acyclovir, tenofovir) was replaced by the P–CH(2)–HN–C(O)– residue. The respective phosphonates were synthesized in good yields by coupling the s...
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| Vydáno v: | Monatsh Chem |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer Vienna
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5101293/ https://ncbi.nlm.nih.gov/pubmed/27881885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1848-x |
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