Acyclic nucleoside phosphonates containing the amide bond

ABSTRACT: To study the influence of a linker rigidity and donor–acceptor properties, the P–CH(2)–O–CHR– fragment in acyclic nucleoside phosphonates (e.g., acyclovir, tenofovir) was replaced by the P–CH(2)–HN–C(O)– residue. The respective phosphonates were synthesized in good yields by coupling the s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Monatsh Chem
Egile Nagusiak: Głowacka, Iwona E., Piotrowska, Dorota G., Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Wróblewski, Andrzej E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Vienna 2016
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101293/
https://ncbi.nlm.nih.gov/pubmed/27881885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1848-x
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