Acyclic nucleoside phosphonates containing the amide bond: hydroxy derivatives

ABSTRACT: To study the influence of a linker rigidity and changes in donor–acceptor properties, three series of nucleotide analogs containing a P–X–HN–C(O)– residue (X=CH(OH)CH(2), CH(OH)CH(2)CH(2), CH(2)CH(OH)CH(2)) as a replacement for the P–CH(2)–O–CHR– fragment in acyclic nucleoside phosphonates...

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Detalhes bibliográficos
Publicado no:Monatsh Chem
Main Authors: Głowacka, Iwona E., Piotrowska, Dorota G., Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Wróblewski, Andrzej E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2019
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087949/
https://ncbi.nlm.nih.gov/pubmed/32214483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-019-2351-y
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