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Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues

The efficient synthesis of a new series of polyhydroxylated dibenzyl ω-(1H-1,2,3-triazol-1-yl)alkylphosphonates as acyclic nucleotide analogues is described starting from dibenzyl ω-azido(polyhydroxy)alkylphosphonates and selected alkynes under microwave irradiation. Selected O,O-dibenzylphosphonate...

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Detaylı Bibliyografya
Yayımlandı:Bioorg Med Chem
Asıl Yazarlar: Głowacka, Iwona E., Balzarini, Jan, Andrei, Graciela, Snoeck, Robert, Schols, Dominique, Piotrowska, Dorota G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Ltd. 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127666/
https://ncbi.nlm.nih.gov/pubmed/24906510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.05.020
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