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Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3‐Triazole Nucleosides

A new strategy for the synthesis of N (3)‐benzoylated‐ and N (3)‐benzylated N (1)‐propargylquinazoline‐2,4‐diones 30a−d and 31a−d from isatoic anhydride 41 is reported. The alkynes 30a−d and 31a−d were applied in the 1,3‐dipolar cycloadditions with azides 27 and 28 to synthesize acyclic 1,2,3‐triazo...

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Detalhes bibliográficos
Publicado no:Arch Pharm (Weinheim)
Main Authors: Głowacka, Iwona E., Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Gawron, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161868/
https://ncbi.nlm.nih.gov/pubmed/28763115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ardp.201700166
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