Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures

Cycloadditions of N-substituted C-(diethoxyphosphoryl)nitrones to N-allylated quinazoline-2,4-diones functionalized at N3 with substituted benzoyl or benzyl groups proceeded with moderate to good diastereoselectivities (d.e. 28–68%). The synthesized isoxazolidine phosphonates were assessed for the a...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Eur J Med Chem
Huvudupphovsmän: Piotrowska, Dorota G., Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Łysakowska, Magdalena
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier Masson SAS. 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125519/
https://ncbi.nlm.nih.gov/pubmed/27750154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.10.002
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk