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Allosteric linkers in cAMP signalling

Weak interactions mediated by dynamic linkers are key determinants of allosteric regulation in multidomain signalling proteins. However, the mechanisms of linker-dependent control have remained largely elusive. In the present article, we review an allosteric model introduced recently to explain how...

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Vydáno v:Biochem Soc Trans
Hlavní autoři: Akimoto, Madoka, Moleschi, Kody, Boulton, Stephen, VanSchouwen, Bryan, Selvaratnam, Rajeevan, Taylor, Susan S., Melacini, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100742/
https://ncbi.nlm.nih.gov/pubmed/24450641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130257
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