Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress

Unregulated growth and replication as well as an abnormal microenvironment, leads to elevated levels of stress which is a common trait of cancer. By inducing both energy and endoplasmic reticulum (ER) stress, 2-Deoxy-glucose (2-DG) is particularly well-suited to take advantage of the therapeutic win...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Liu, Huaping, Kurtoglu, Metin, León-Annicchiarico, Clara Lucia, Munoz-Pinedo, Cristina, Barredo, Julio, Leclerc, Guy, Merchan, Jaime, Liu, Xiongfei, Lampidis, Theodore J.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095013/
https://ncbi.nlm.nih.gov/pubmed/27183907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9263
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