Autophagy maintains ubiquitination-proteasomal degradation of Sirt3 to limit oxidative stress in K562 leukemia cells

Sirtuin protein family member 3 (Sirt3) has been suggested as a positive regulator in alleviating oxidative stress by acting on the mitochondrial antioxidant machinery in solid tumors; however, its role and regulation in hematological malignancies has been poorly understood. Here, we show that contr...

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Pubblicato in:Oncotarget
Autori principali: Fang, Yixuan, Wang, Jian, Xu, Li, Cao, Yan, Xu, Fei, Yan, Lili, Nie, Meilan, Yuan, Na, Zhang, Suping, Zhao, Ruijin, Wang, Hongbin, Wu, Mengyin, Zhang, Xiaoying, Wang, Jianrong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper: Autophagy and Cell Death
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094955/
https://ncbi.nlm.nih.gov/pubmed/27232755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9592
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