Erythroleukemia cells acquire an alternative mitophagy capability

Leukemia cells are superior to hematopoietic cells with a normal differentiation potential in buffering cellular stresses, but the underlying mechanisms for this leukemic advantage are not fully understood. Using CRISPR/Cas9 deletion of the canonical autophagy-essential gene Atg7, we found that eryt...

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Udgivet i:Sci Rep
Main Authors: Wang, Jian, Fang, Yixuan, Yan, Lili, Yuan, Na, Zhang, Suping, Xu, Li, Nie, Meilan, Zhang, Xiaoying, Wang, Jianrong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835698/
https://ncbi.nlm.nih.gov/pubmed/27091640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24641
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