Autophagy confers DNA damage repair pathways to protect the hematopoietic system from nuclear radiation injury

Autophagy is essentially a metabolic process, but its in vivo role in nuclear radioprotection remains unexplored. We observed that ex vivo autophagy activation reversed the proliferation inhibition, apoptosis, and DNA damage in irradiated hematopoietic cells. In vivo autophagy activation improved bo...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Sci Rep
Main Authors: Lin, Weiwei, Yuan, Na, Wang, Zhen, Cao, Yan, Fang, Yixuan, Li, Xin, Xu, Fei, Song, Lin, Wang, Jian, Zhang, Han, Yan, Lili, Xu, Li, Zhang, Xiaoying, Zhang, Suping, Wang, Jianrong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2015
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508834/
https://ncbi.nlm.nih.gov/pubmed/26197097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12362
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla