Autophagy‐Sirt3 axis decelerates hematopoietic aging

Autophagy suppresses mitochondrial metabolism to preserve hematopoietic stem cells (HSCs) in mice. However, the mechanism by which autophagy regulates hematopoietic aging, in particular in humans, has largely been unexplored. Here, we demonstrate that reduction of autophagy in both hematopoietic cel...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Fang, Yixuan, An, Ni, Zhu, Lingjiang, Gu, Yue, Qian, Jiawei, Jiang, Gaoyue, Zhao, Ruijin, Wei, Wen, Xu, Li, Zhang, Gaochuan, Yao, Xingyun, Yuan, Na, Zhang, Suping, Zhao, Yun, Wang, Jianrong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576273/
https://ncbi.nlm.nih.gov/pubmed/32951306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13232
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