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Autophagy‐Sirt3 axis decelerates hematopoietic aging
Autophagy suppresses mitochondrial metabolism to preserve hematopoietic stem cells (HSCs) in mice. However, the mechanism by which autophagy regulates hematopoietic aging, in particular in humans, has largely been unexplored. Here, we demonstrate that reduction of autophagy in both hematopoietic cel...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7576273/ https://ncbi.nlm.nih.gov/pubmed/32951306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13232 |
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