Autophagy‐Sirt3 axis decelerates hematopoietic aging

Autophagy suppresses mitochondrial metabolism to preserve hematopoietic stem cells (HSCs) in mice. However, the mechanism by which autophagy regulates hematopoietic aging, in particular in humans, has largely been unexplored. Here, we demonstrate that reduction of autophagy in both hematopoietic cel...

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Publicat a:Aging Cell
Autors principals: Fang, Yixuan, An, Ni, Zhu, Lingjiang, Gu, Yue, Qian, Jiawei, Jiang, Gaoyue, Zhao, Ruijin, Wei, Wen, Xu, Li, Zhang, Gaochuan, Yao, Xingyun, Yuan, Na, Zhang, Suping, Zhao, Yun, Wang, Jianrong
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576273/
https://ncbi.nlm.nih.gov/pubmed/32951306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13232
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