Učitavanje...
RNA splicing factors as oncoproteins and tumor suppressors
The recent genomic characterization of cancers has revealed recurrent somatic point mutations and copy number changes affecting genes encoding RNA splicing factors. Initial studies of these ‘spliceosomal mutations’ suggest that the proteins bearing these mutations exhibit altered splice site and/or...
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| Izdano u: | Nat Rev Cancer |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094465/ https://ncbi.nlm.nih.gov/pubmed/27282250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2016.51 |
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