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Therapeutic modulation of RNA splicing in malignant and non-malignant disease

RNA splicing is the enzymatic process by which non-protein coding sequences are removed from RNA to produce mature protein coding messenger RNA (mRNA). Splicing is thereby a major mediator of proteome diversity as well as a dynamic regulator of gene expression. Genetic alterations disrupting splicin...

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Detalhes bibliográficos
Publicado no:Trends Mol Med
Main Authors: El Marabti, Ettaib, Abdel-Wahab, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238868/
https://ncbi.nlm.nih.gov/pubmed/33994320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2021.04.005
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