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Therapeutic modulation of RNA splicing in malignant and non-malignant disease
RNA splicing is the enzymatic process by which non-protein coding sequences are removed from RNA to produce mature protein coding messenger RNA (mRNA). Splicing is thereby a major mediator of proteome diversity as well as a dynamic regulator of gene expression. Genetic alterations disrupting splicin...
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| Published in: | Trends Mol Med |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8238868/ https://ncbi.nlm.nih.gov/pubmed/33994320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2021.04.005 |
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