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RNA splicing factors as oncoproteins and tumor suppressors
The recent genomic characterization of cancers has revealed recurrent somatic point mutations and copy number changes affecting genes encoding RNA splicing factors. Initial studies of these ‘spliceosomal mutations’ suggest that the proteins bearing these mutations exhibit altered splice site and/or...
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| Publicado no: | Nat Rev Cancer |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094465/ https://ncbi.nlm.nih.gov/pubmed/27282250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2016.51 |
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