Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver

Transcription of the gene encoding sterol regulatory element-binding protein 1c (SREBP-1c) is known to be activated by insulin in the liver. The resultant SREBP-1c protein activates transcription of the genes required for fatty acid synthesis. Here, we use SREBP-1c promoter reporter constructs to di...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chen, Guoxun, Liang, Guosheng, Ou, Jiafu, Goldstein, Joseph L., Brown, Michael S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2004
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC509189/
https://ncbi.nlm.nih.gov/pubmed/15266058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404297101
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia