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Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis
Insig-1 and -2 are closely related proteins of the endoplasmic reticulum (ER) that block proteolytic activation of sterol regulatory element-binding proteins (SREBPs), transcription factors that activate the synthesis of cholesterol and fatty acids in liver and other organs. When cellular cholestero...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152262/ https://ncbi.nlm.nih.gov/pubmed/12624180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0130116100 |
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