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Insig Proteins Mediate Feedback Inhibition of Cholesterol Synthesis in the Intestine

Enterocytes are the only cell type that must balance the de novo synthesis and absorption of cholesterol, although the coordinate regulation of these processes is not well understood. Our previous studies demonstrated that enterocytes respond to the pharmacological blockade of cholesterol absorption...

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Bibliographic Details
Main Authors: McFarlane, Matthew R., Liang, Guosheng, Engelking, Luke J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900961/
https://ncbi.nlm.nih.gov/pubmed/24337570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.524041
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