GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity

Adoptive T-cell therapy (ACT) is an emerging paradigm in which T cells are genetically modified to target cancer-associated antigens and eradicate tumors. However, challenges treating epithelial cancers with ACT reflect antigen targets that are not tumor-specific, permitting immune damage to normal...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncoimmunology
Autors principals: Magee, Michael S., Kraft, Crystal L., Abraham, Tara S., Baybutt, Trevor R., Marszalowicz, Glen P., Li, Peng, Waldman, Scott A., Snook, Adam E.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087292/
https://ncbi.nlm.nih.gov/pubmed/27853651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1227897
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars