GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity

Adoptive T-cell therapy (ACT) is an emerging paradigm in which T cells are genetically modified to target cancer-associated antigens and eradicate tumors. However, challenges treating epithelial cancers with ACT reflect antigen targets that are not tumor-specific, permitting immune damage to normal...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncoimmunology
Päätekijät: Magee, Michael S., Kraft, Crystal L., Abraham, Tara S., Baybutt, Trevor R., Marszalowicz, Glen P., Li, Peng, Waldman, Scott A., Snook, Adam E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2016
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087292/
https://ncbi.nlm.nih.gov/pubmed/27853651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1227897
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