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GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity
Adoptive T-cell therapy (ACT) is an emerging paradigm in which T cells are genetically modified to target cancer-associated antigens and eradicate tumors. However, challenges treating epithelial cancers with ACT reflect antigen targets that are not tumor-specific, permitting immune damage to normal...
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| 發表在: | Oncoimmunology |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087292/ https://ncbi.nlm.nih.gov/pubmed/27853651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1227897 |
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