Carregant...
β Cell–specific increased expression of calpastatin prevents diabetes induced by islet amyloid polypeptide toxicity
The islet in type 2 diabetes (T2D) shares many features of the brain in protein misfolding diseases. There is a deficit of β cells with islet amyloid derived from islet amyloid polypeptide (IAPP), a protein coexpressed with insulin. Small intracellular membrane-permeant oligomers, the most toxic for...
Guardat en:
| Publicat a: | JCI Insight |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2016
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5085608/ https://ncbi.nlm.nih.gov/pubmed/27812546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89590 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|