Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo.

Cationic lipids show promise as vectors for transfer of CFTR cDNA to airway epithelia of patients with cystic fibrosis (CF). However, previous studies have not compared the effect of DNA-lipid to DNA alone. Recently, we developed a formulation of plasmid encoding CFTR (pCF1-CFTR) and cationic lipid...

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Hauptverfasser: Zabner, J, Cheng, S H, Meeker, D, Launspach, J, Balfour, R, Perricone, M A, Morris, J E, Marshall, J, Fasbender, A, Smith, A E, Welsh, M J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508334/
https://ncbi.nlm.nih.gov/pubmed/9294121
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