Human cystic fibrosis airway epithelia have reduced Cl(−) conductance but not increased Na(+) conductance

Loss of cystic fibrosis transmembrane conductance regulator (CFTR) anion channel function causes cystic fibrosis (CF) lung disease. CFTR is expressed in airway epithelia, but how CF alters electrolyte transport across airway epithelia has remained uncertain. Recent studies of a porcine model showed...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Itani, Omar A., Chen, Jeng-Haur, Karp, Philip H., Ernst, Sarah, Keshavjee, Shaf, Parekh, Kalpaj, Klesney-Tait, Julia, Zabner, Joseph, Welsh, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121869/
https://ncbi.nlm.nih.gov/pubmed/21646513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106695108
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge