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MMP9 modulates tight junction integrity and cell viability in human airway epithelia

The family of zinc- and calcium-dependent matrix metalloproteases (MMPs) play an important role in remodeling of the airways in disease. Transcriptional regulation by proinflammatory cytokines increases lymphocyte-derived MMP9 levels in the airway lumen of asthmatics. Moreover, the levels of the MMP...

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Detalhes bibliográficos
Main Authors: Vermeer, Paola D., Denker, James, Estin, Miriam, Moninger, Thomas O., Keshavjee, Shaf, Karp, Philip, Kline, Joel N., Zabner, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681350/
https://ncbi.nlm.nih.gov/pubmed/19270179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90578.2008
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