cAMP stimulates bicarbonate secretion across normal, but not cystic fibrosis airway epithelia.

Adenosine 3',5'-cyclic monophosphate stimulates chloride (Cl-) secretion across airway epithelia. To determine whether cAMP also stimulates HCO3- secretion, we studied cultured canine and human airway epithelial cells bathed in a HCO3-/CO2-buffered, Cl(-)-free solution. Addition of forskol...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Smith, J J, Welsh, M J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442972/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313448/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115696
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