Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo.

Cationic lipids show promise as vectors for transfer of CFTR cDNA to airway epithelia of patients with cystic fibrosis (CF). However, previous studies have not compared the effect of DNA-lipid to DNA alone. Recently, we developed a formulation of plasmid encoding CFTR (pCF1-CFTR) and cationic lipid...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zabner, J, Cheng, S H, Meeker, D, Launspach, J, Balfour, R, Perricone, M A, Morris, J E, Marshall, J, Fasbender, A, Smith, A E, Welsh, M J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508334/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294121/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119676
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