Selective Degeneration of Entorhinal-CA1 Synapses in Alzheimer's Disease via Activation of DAPK1

Excitatory pyramidal neurons in the entorhinal cortical layer II region (ECII(PN)) form functional excitatory synapses with CA1 parvalbumin inhibitory neurons (CA1(PV)) and undergo selective degeneration in the early stages of Alzheimer's disease (AD). Here, we show that death-associated protei...

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Publicat a:J Neurosci
Autors principals: Shu, Shu, Zhu, Houze, Tang, Na, Chen, Wenting, Li, Xinyan, Li, Hao, Pei, Lei, Liu, Dan, Mu, Yangling, Tian, Qing, Zhu, Ling-Qiang, Lu, Youming
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083012/
https://ncbi.nlm.nih.gov/pubmed/27798139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2258-16.2016
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