DAPK1–p53 Interaction Converges Necrotic and Apoptotic Pathways of Ischemic Neuronal Death

Necrosis and apoptosis are two distinct types of mechanisms that mediate ischemic injury. But a signaling point of convergence between them has yet to be identified. Here, we show that activated death-associated protein kinase 1 (DAPK1), phosphorylates p53 at serine-23 (pS(23)) via a direct binding...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Pei, Lei, Shang, You, Jin, Huijuan, Wang, Shan, Wei, Na, Yan, Honglin, Wu, Yan, Yao, Chengye, Wang, Xiaoxi, Zhu, Ling-Qiang, Lu, Youming
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608141/
https://ncbi.nlm.nih.gov/pubmed/24806680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5119-13.2014
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