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Dual anti-ischemic effects of rosmarinic acid n-butyl ester via alleviation of DAPK-p53-mediated neuronal damage and microglial inflammation

The discovery of efficacious anti-ischemic drugs remains a challenge. Recently we have found that rosmarinic acid n-butyl ester (RABE), a derivative of rosmarinic acid, significantly protects SH-SY5Y cells against oxygen glucose deprivation (OGD)-induced cell death. In the present study we simultane...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Wu, Lei, Wang, Hong-min, Li, Jin-long, Feng, Hong-xuan, Zhao, Wei-min, Zhang, Hai-yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533207/
https://ncbi.nlm.nih.gov/pubmed/28216621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.156
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