Selective Degeneration of Entorhinal-CA1 Synapses in Alzheimer's Disease via Activation of DAPK1

Excitatory pyramidal neurons in the entorhinal cortical layer II region (ECII(PN)) form functional excitatory synapses with CA1 parvalbumin inhibitory neurons (CA1(PV)) and undergo selective degeneration in the early stages of Alzheimer's disease (AD). Here, we show that death-associated protei...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Shu, Shu, Zhu, Houze, Tang, Na, Chen, Wenting, Li, Xinyan, Li, Hao, Pei, Lei, Liu, Dan, Mu, Yangling, Tian, Qing, Zhu, Ling-Qiang, Lu, Youming
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083012/
https://ncbi.nlm.nih.gov/pubmed/27798139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2258-16.2016
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