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Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles.

Previous studies showed that transgenic mice overexpressing either apolipoprotein AI (apoAI) or apolipoprotein AII (apoAII), the major proteins of HDL, exhibited elevated levels of HDL cholesterol, but, whereas the apoAI-transgenic mice were protected against atherosclerosis, the apoAII-transgenic m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Castellani, L W, Navab, M, Van Lenten, B J, Hedrick, C C, Hama, S Y, Goto, A M, Fogelman, A M, Lusis, A J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508211/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9218525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119554
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