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Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B.

We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma cholesterol and triglyceride levels due to the disappearance of VLDL and LDL. In this study, we investigated the metabolism of plasma lipoproteins in transgenic mice. After intravenous injection, the rate...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Shimano, H, Yamada, N, Katsuki, M, Yamamoto, K, Gotoda, T, Harada, K, Shimada, M, Yazaki, Y
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443275/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1430232/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116091
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