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Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B.

We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma cholesterol and triglyceride levels due to the disappearance of VLDL and LDL. In this study, we investigated the metabolism of plasma lipoproteins in transgenic mice. After intravenous injection, the rate...

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Detalhes bibliográficos
Main Authors: Shimano, H, Yamada, N, Katsuki, M, Yamamoto, K, Gotoda, T, Harada, K, Shimada, M, Yazaki, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC443275/
https://ncbi.nlm.nih.gov/pubmed/1430232
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