Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B.

We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma cholesterol and triglyceride levels due to the disappearance of VLDL and LDL. In this study, we investigated the metabolism of plasma lipoproteins in transgenic mice. After intravenous injection, the rate...

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Pubblicato in:	J Clin Invest
Autori principali:	Shimano, H, Yamada, N, Katsuki, M, Yamamoto, K, Gotoda, T, Harada, K, Shimada, M, Yazaki, Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1430232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116091
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