Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.

We have generated transgenic mice expressing the human apolipoprotein CII (apoCII) gene under the transcriptional control of the human cytochrome P-450 IA1 (CYPIA1) promoter. Human apoCII transgenic (HuCIITg) mice exhibited significant basal expression of the transgene (plasma apoCII level = 26.1 +/...

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Main Authors: Shachter, N S, Hayek, T, Leff, T, Smith, J D, Rosenberg, D W, Walsh, A, Ramakrishnan, R, Goldberg, I J, Ginsberg, H N, Breslow, J L
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC294216/
https://ncbi.nlm.nih.gov/pubmed/8163669
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