Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.

We have generated transgenic mice expressing the human apolipoprotein CII (apoCII) gene under the transcriptional control of the human cytochrome P-450 IA1 (CYPIA1) promoter. Human apoCII transgenic (HuCIITg) mice exhibited significant basal expression of the transgene (plasma apoCII level = 26.1 +/...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Shachter, N S, Hayek, T, Leff, T, Smith, J D, Rosenberg, D W, Walsh, A, Ramakrishnan, R, Goldberg, I J, Ginsberg, H N, Breslow, J L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294216/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8163669/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117151
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!