Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles.
Previous studies showed that transgenic mice overexpressing either apolipoprotein AI (apoAI) or apolipoprotein AII (apoAII), the major proteins of HDL, exhibited elevated levels of HDL cholesterol, but, whereas the apoAI-transgenic mice were protected against atherosclerosis, the apoAII-transgenic m...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508211/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9218525/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119554 |
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