Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles.

Previous studies showed that transgenic mice overexpressing either apolipoprotein AI (apoAI) or apolipoprotein AII (apoAII), the major proteins of HDL, exhibited elevated levels of HDL cholesterol, but, whereas the apoAI-transgenic mice were protected against atherosclerosis, the apoAII-transgenic m...

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Detalhes bibliográficos
Main Authors: Castellani, L W, Navab, M, Van Lenten, B J, Hedrick, C C, Hama, S Y, Goto, A M, Fogelman, A M, Lusis, A J
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508211/
https://ncbi.nlm.nih.gov/pubmed/9218525
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