Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles.

Previous studies showed that transgenic mice overexpressing either apolipoprotein AI (apoAI) or apolipoprotein AII (apoAII), the major proteins of HDL, exhibited elevated levels of HDL cholesterol, but, whereas the apoAI-transgenic mice were protected against atherosclerosis, the apoAII-transgenic m...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Castellani, L W, Navab, M, Van Lenten, B J, Hedrick, C C, Hama, S Y, Goto, A M, Fogelman, A M, Lusis, A J
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508211/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9218525/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119554
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