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Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release
Goblet cell hyperplasia, a feature of asthma and other respiratory diseases, is driven by the Th-2 cytokines IL-4 and IL-13. In human bronchial epithelial cells, we find that IL-4 induces the expression of many genes coding for ion channels and transporters, including TMEM16A, SLC26A4, SLC12A2, and...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081536/ https://ncbi.nlm.nih.gov/pubmed/27786259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36016 |
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