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Drug-set enrichment analysis: a novel tool to investigate drug mode of action

Motivation: Automated screening approaches are able to rapidly identify a set of small molecules inducing a desired phenotype from large small-molecule libraries. However, the resulting set of candidate molecules is usually very diverse pharmacologically, thus little insight on the shared mechanism...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformatics
Prif Awduron: Napolitano, Francesco, Sirci, Francesco, Carrella, Diego, di Bernardo, Diego
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795590/
https://ncbi.nlm.nih.gov/pubmed/26415724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv536
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